1 USD
=
2110 MMK
1 USD =
2110 MMK
FAME Mangosteen Anti-cancer supplement (60s)
ကုန်ပစ္စည်းအကြောင်းအရာ :
Composition:
Each tablet contains:
Extract of Garcinia mangostana pericarp containing xanthones ....200 mg
Phytochemistry:
Approximately 40 of over 200 naturally occurring xanthones are found in Garcinia mangostana (mangosteen). The most studied xanthones are α-, β- and γ-mangostins, garcinone E, 8-deoxygartanin and gartanin. They possess antioxidant, anti-tumoral, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal and anti-viral properties.
Pharmacological actions:
Anti-microbial activities
The extract from mangosteen pericarp has broad spectrum anti-bacterial activity against several Gram-positive and Gram-negative bacteria. S.aureus, P.aeruginosa, S.typhimurium and B.subtillis were highly susceptible to xanthones. The investigators from Gifu Pharmaceutical University, Japan showed that the anti-bacterial activity of xanthone derivatives of Mangosteen against both methicillin resistant and methicillin sensitive S.aureus. MIC of α-mangostin was between 12.5 and 50 µg/ml for bacterial and between 1 and 5 µg/ml for fungi. α- and β-mangostin and garcinone B exhibited the most potent inhibitory effect against Mycobacterium tuberculosis with MIC of 6.25 µg/ml
Anti-allergic action
Chairungsrilered et al.(1996) determined that α- and γ-mangostin are histaminergic and serotonergic receptor blocking agents respectively. Nakatani et al.(2002) also found that mangosteen fruit extract strongly inhibited histamine release and prostaglandin E2 synthesis.
Anti-inflammatory action
α-mangostin attenuates expression of inflammatory mediators such as TNF-α and IL-6. Garcinone B interferes with activation of NF-κB. Conversion of arachidonic acid to PGE2 was inhibited by γ-mangostin which also inhibited the activities of both COX-1 and COX-2. Ingestion of a blended mangosteen juice decreased serum C-reactive protein levels.
Anti-tumor activities
The anti-tumor activities of xanthones include cell cycle arrest, suppression of tumor cell proliferation, induction of apoptosis and differentiation, reduction of inflammation and inhibition of adhesion, invasion and metastasis. At relatively low dose of mangosteen xanthones, the growth of tumors was delayed. When treated with a high dose of xanthones, tumor size gradually decreased and complete regressions occurred.
ကုန်ပစ္စည်းအင်္ဂါရပ်များ :
◆ Natural antibiotics
◆ Ease allergic responses
◆ Reduce inflammation
◆ Suppress abnormal cell growth
ပါဝင်သည့်ပစ္စည်းများ :
-60 tablets per bottle
ကုန်ပစ္စည်းအကြောင်းအရာ :
Composition:
Each tablet contains:
Extract of Garcinia mangostana pericarp containing xanthones ....200 mg
Phytochemistry:
Approximately 40 of over 200 naturally occurring xanthones are found in Garcinia mangostana (mangosteen). The most studied xanthones are α-, β- and γ-mangostins, garcinone E, 8-deoxygartanin and gartanin. They possess antioxidant, anti-tumoral, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal and anti-viral properties.
Pharmacological actions:
Anti-microbial activities
The extract from mangosteen pericarp has broad spectrum anti-bacterial activity against several Gram-positive and Gram-negative bacteria. S.aureus, P.aeruginosa, S.typhimurium and B.subtillis were highly susceptible to xanthones. The investigators from Gifu Pharmaceutical University, Japan showed that the anti-bacterial activity of xanthone derivatives of Mangosteen against both methicillin resistant and methicillin sensitive S.aureus. MIC of α-mangostin was between 12.5 and 50 µg/ml for bacterial and between 1 and 5 µg/ml for fungi. α- and β-mangostin and garcinone B exhibited the most potent inhibitory effect against Mycobacterium tuberculosis with MIC of 6.25 µg/ml
Anti-allergic action
Chairungsrilered et al.(1996) determined that α- and γ-mangostin are histaminergic and serotonergic receptor blocking agents respectively. Nakatani et al.(2002) also found that mangosteen fruit extract strongly inhibited histamine release and prostaglandin E2 synthesis.
Anti-inflammatory action
α-mangostin attenuates expression of inflammatory mediators such as TNF-α and IL-6. Garcinone B interferes with activation of NF-κB. Conversion of arachidonic acid to PGE2 was inhibited by γ-mangostin which also inhibited the activities of both COX-1 and COX-2. Ingestion of a blended mangosteen juice decreased serum C-reactive protein levels.
Anti-tumor activities
The anti-tumor activities of xanthones include cell cycle arrest, suppression of tumor cell proliferation, induction of apoptosis and differentiation, reduction of inflammation and inhibition of adhesion, invasion and metastasis. At relatively low dose of mangosteen xanthones, the growth of tumors was delayed. When treated with a high dose of xanthones, tumor size gradually decreased and complete regressions occurred.
ကုန်ပစ္စည်းအင်္ဂါရပ်များ :
◆ Natural antibiotics
◆ Ease allergic responses
◆ Reduce inflammation
◆ Suppress abnormal cell growth
ပါဝင်သည့်ပစ္စည်းများ :
-60 tablets per bottle
Delivery အချက်အလက် :
တစ်နိုင်ငံလုံးပို့ဆောင်ခအသက်သာဆုံးနှင့် အရွယ်အစား (၂ပေပတ်လည်အောက်)ပစ္စည်းများ ပစ္စည်းရောက်ငွေချေနိုင်သော(CODစနစ်) ဖြင့် 3 ရက်မှ 10 ရက်အတွင်း သင့်အိမ်ရှေ့အရောက် မှာယူတဲ့ပစ္စည်းလေး ရောက်ရှိလာပါမယ်။
ဘယ်လို၀ယ်ရမလဲ :
ဘယ်လိုရောင်းရမလဲ :
ပြန်လည်ပေးပို့ခြင်းမူဝါဒ :
ပစၥည္းအမွားအယြင္းတစံုတရာ ရွိပါက ပစၥည္းေရာက္ရွိၿပီး တရက္အတြင္း အေၾကာင္းၾကား၍ ပစၥည္းျပန္လည္ပို႔ေဆာင္ေပးလွ်င္ အသစ္ျပန္လဲ ေပးမွာျဖစ္ပါတယ္။ ( ပစၥည္းအသစ္အေနအထား ယိုယြင္းပ်က္စီးေနပါက လဲလွယ္ေပးမည္ မဟုတ္ပါ ) ေငြျပန္အမ္းျခင္းသီးခံပါ။